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VC3 – Pressurized Perfusion System for Focal Perfusion

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VC3 – Pressurized Perfusion System

  • Easy to use valve control with TTL, analog, PC or pushbuttons
  • Low volume application
  • Rapid solution exchange
  • Different perfusion outlets for various flow rates and spatial precision
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Details

Each VC3-P Series system includes the following:

  • Magnetic stand with poles
  • Valve manifold with solenoid or pinch valves and 5mL pressurized syringe reservoirs
  • VC3 electronic valve controller with a USB cable and Valve Commander software
  • DB9-CABLE controller to valve manifold cable
  • Spill sensor and tubing

Each VC3P Series system features a choice of valves:

  • Pinch valves : The 3-way normally open and normally closed pinch valves require minimal maintenance in long-term perfusion experiments and have response times of 15-20 ms.
  • Isolation valves : The 2-way normally closed solenoid valves are optimized for high-speed solution exchange. These valves feature a biologically inert internally wettable surface (PTFE) and have response times of 2 to 5 ms.

Clippard isolation valve

 

3 way pinch valve

 

 

 

 

 

 

Additional options include:

  • Spill sensor
  • BOB-8 connection box for TTL trigger inputs / outputs

Ordering

Part No. Description
ALA VC3-xPP (x = 4 or 8) 4 or 8 channel Pressurized Perfusion System: pinch valves, magnetic stand with poles, valve manifold, 5mL pressurized reservoirs, VC3 electronic valve controller and power supply, spill sensor, tubing, cables and software
ALA VC3-xCLP (x = 4 or 8) 4 or 8 channel Pressurized Perfusion System: Clippard isolation valves, magnetic stand with poles, valve manifold, 5mL pressurized reservoirs, VC3 electronic valve controller and power supply, spill sensor, tubing, cables and software
ALA VC3-xC (x = 4 or 8) 4 or 8 channel VC3 electronic valve controller including power supply, cables and software
ALA VC3-PS VC3 electronic valve controller power supply
ALA QMM-x (x = 4 or 8) Quartz MicroManifold® 4 or 8 to 1 channel perfusion outlet manifold with 100um or 200um ID (please specify) tubing and tip (other sizes available – please call or email to inquire)
ALA QMM-xWT (x = 4 or 8) Quartz MicroManifold® 4 or 8 to 1 perfusion outlet manifold with 100um or 200um ID (please specify) tubing and tip (other sizes available – please call or email to inquire) and clear teflon tubing installed
ALA MLF-x (x = 4 or 8) MilliManifold 4 or 8 to 1 channel perfusion outlet manifold made of 500um ID polyimide tubing with 1/16″ barb fittings
ALA 60mlRES 60mL pressurized reservoir assembly with 3-way luer valve
ALA 10mlRES 10mL pressurized reservoir assembly with 3-way luer valve
ALA 5mlRES 5mL pressurized reservoir assembly with 3-way luer valve
ALA PV Replacement pinch valve
ALA L2V Replacement solenoid valve
ALA DB9-CABLE Replacement VC3 controller to valve manifold cable
ALA DB9F-BNC8 Replacement TTL trigger to 4-BNC cable
ALA VM-STAND Replacement valve manifold stand: magnetic base and 2 rods
ALA VC3xAIRMAN (x = 4 or 8) Replacement pressurized air manifold tubing set
ALA SPILSNSR Replacement Lasso Spill Sensor with connector
ALA FEP-1 4m clear Teflon tubing with 230um ID and 600um OD (for 100um ID QMM’s)
ALA FEP-2 4m clear Teflon tubing with 380um ID and 760um OD (for 200um ID QMM’s)
ALA CF-1 Compression fitting for PE-10/FEP-1 tubing to 1/16″ ID tubing
ALA CF-2 Compression fitting for PE-20/FEP-2 tubing to 1/16″ ID tubing
ALA TUBING-2 10′ 1/16″ ID and 1/8″ OD PVC tubing
ALA TUBING-4 2′ silicone pinch valve tubing for pressurized flow

 

Accessories

MLF-x (x = 4 or 8) MilliManifold 4 or 8 channel perfusion outlet manifold
QMM-x (x = 4 or 8) Quartz MicroManifold® 4 or 8 channel perfusion outlet manifold for low dead-volumes
Compression Fittings adaptors for tubing of different outer diameters
Magnetic perfusion in- / outlets and holders Adjustable perfusion canulas, tool holders, etc.
PR-10 0-10 psi analog two-stage pressure regulator

 

Technical Data

Valve Controller:

    • Dimensions/Weight: 8″/20.32cm x 6″/15.24cm x 2.5″/6.35cm / 1.5lbs/0.68kg
    • Power: 15VDC/3.15A
    • Computer Control Input: Analog input 0.5V/valve[ TTL high 1 bit/valve; USB 2.0
    • Computer Output Monitoring: Analog output 0.5V/valve; Sync TTL high; TTL high 1 bit/valve
    • Manual Control: Membrane switch 1/valve; mom on/off or toggle on/off

Valve Manifolds:

    • Pinch Valves: 12VDC/0.25A each- 3-way normally open or normally closed pinch valves
    • Pinch Valve Opening Speed: 15 to 20 ms
    • Pinch Valve ID Tubing: 0.020″/0.5mm
    • Solenoid Valves: 12VDC/0.25A each- Lee OEM Inert Solenoid Valve
    • Solenoid Valve Opening Speed: 1-2 ms
    • Reservoirs : 5mL pressurized syringes with 3-way stop cock luer valves

Sample pressurized flow rate: 1mL in 9 minutes @ 10 PSI / 70kPa through QMM with 100μm ID tubes

ABOUT

The VC3-P Series from ALA includes 4 or 8 channel valve controlled pressurized perfusion systems for focal perfusion. The system can fulfill the basic requirements of the student lab, but can also be optimized to fit the most demanding applications of patch clamp recording and/or imaging. All VC3-xxP Series systems provide electronic control of solution exchange, which improves reproducibility over manual methods. These systems are designed to minimize electronic noise so sensitive electrophysiological recordings are not disturbed.

Key features of the VC3-P Series include:

  • Choice of low-maintenance pinch valves or fast-response isolation valves
  • Customizable reservoir sizes and materials
  • External control by the data acquisition system via analog or TTL input signal
  • Valve control through data acquisition system, Valve Commander software, or controller buttons
  • Spill sensor with automatic shutoff to protect other devices in case of leakage
  • Monitor valve open and close timestamps via analog or digital output signal

Details

Details

Each VC3-P Series system includes the following:

  • Magnetic stand with poles
  • Valve manifold with solenoid or pinch valves and 5mL pressurized syringe reservoirs
  • VC3 electronic valve controller with a USB cable and Valve Commander software
  • DB9-CABLE controller to valve manifold cable
  • Spill sensor and tubing

Each VC3P Series system features a choice of valves:

  • Pinch valves : The 3-way normally open and normally closed pinch valves require minimal maintenance in long-term perfusion experiments and have response times of 15-20 ms.
  • Isolation valves : The 2-way normally closed solenoid valves are optimized for high-speed solution exchange. These valves feature a biologically inert internally wettable surface (PTFE) and have response times of 2 to 5 ms.

Clippard isolation valve

 

3 way pinch valve

 

 

 

 

 

 

Additional options include:

  • Spill sensor
  • BOB-8 connection box for TTL trigger inputs / outputs

Ordering

Ordering

Part No. Description
ALA VC3-xPP (x = 4 or 8) 4 or 8 channel Pressurized Perfusion System: pinch valves, magnetic stand with poles, valve manifold, 5mL pressurized reservoirs, VC3 electronic valve controller and power supply, spill sensor, tubing, cables and software
ALA VC3-xCLP (x = 4 or 8) 4 or 8 channel Pressurized Perfusion System: Clippard isolation valves, magnetic stand with poles, valve manifold, 5mL pressurized reservoirs, VC3 electronic valve controller and power supply, spill sensor, tubing, cables and software
ALA VC3-xC (x = 4 or 8) 4 or 8 channel VC3 electronic valve controller including power supply, cables and software
ALA VC3-PS VC3 electronic valve controller power supply
ALA QMM-x (x = 4 or 8) Quartz MicroManifold® 4 or 8 to 1 channel perfusion outlet manifold with 100um or 200um ID (please specify) tubing and tip (other sizes available – please call or email to inquire)
ALA QMM-xWT (x = 4 or 8) Quartz MicroManifold® 4 or 8 to 1 perfusion outlet manifold with 100um or 200um ID (please specify) tubing and tip (other sizes available – please call or email to inquire) and clear teflon tubing installed
ALA MLF-x (x = 4 or 8) MilliManifold 4 or 8 to 1 channel perfusion outlet manifold made of 500um ID polyimide tubing with 1/16″ barb fittings
ALA 60mlRES 60mL pressurized reservoir assembly with 3-way luer valve
ALA 10mlRES 10mL pressurized reservoir assembly with 3-way luer valve
ALA 5mlRES 5mL pressurized reservoir assembly with 3-way luer valve
ALA PV Replacement pinch valve
ALA L2V Replacement solenoid valve
ALA DB9-CABLE Replacement VC3 controller to valve manifold cable
ALA DB9F-BNC8 Replacement TTL trigger to 4-BNC cable
ALA VM-STAND Replacement valve manifold stand: magnetic base and 2 rods
ALA VC3xAIRMAN (x = 4 or 8) Replacement pressurized air manifold tubing set
ALA SPILSNSR Replacement Lasso Spill Sensor with connector
ALA FEP-1 4m clear Teflon tubing with 230um ID and 600um OD (for 100um ID QMM’s)
ALA FEP-2 4m clear Teflon tubing with 380um ID and 760um OD (for 200um ID QMM’s)
ALA CF-1 Compression fitting for PE-10/FEP-1 tubing to 1/16″ ID tubing
ALA CF-2 Compression fitting for PE-20/FEP-2 tubing to 1/16″ ID tubing
ALA TUBING-2 10′ 1/16″ ID and 1/8″ OD PVC tubing
ALA TUBING-4 2′ silicone pinch valve tubing for pressurized flow

 

Accessories

Accessories

MLF-x (x = 4 or 8) MilliManifold 4 or 8 channel perfusion outlet manifold
QMM-x (x = 4 or 8) Quartz MicroManifold® 4 or 8 channel perfusion outlet manifold for low dead-volumes
Compression Fittings adaptors for tubing of different outer diameters
Magnetic perfusion in- / outlets and holders Adjustable perfusion canulas, tool holders, etc.
PR-10 0-10 psi analog two-stage pressure regulator

 

Technical Data

Technical Data

Valve Controller:

    • Dimensions/Weight: 8″/20.32cm x 6″/15.24cm x 2.5″/6.35cm / 1.5lbs/0.68kg
    • Power: 15VDC/3.15A
    • Computer Control Input: Analog input 0.5V/valve[ TTL high 1 bit/valve; USB 2.0
    • Computer Output Monitoring: Analog output 0.5V/valve; Sync TTL high; TTL high 1 bit/valve
    • Manual Control: Membrane switch 1/valve; mom on/off or toggle on/off

Valve Manifolds:

    • Pinch Valves: 12VDC/0.25A each- 3-way normally open or normally closed pinch valves
    • Pinch Valve Opening Speed: 15 to 20 ms
    • Pinch Valve ID Tubing: 0.020″/0.5mm
    • Solenoid Valves: 12VDC/0.25A each- Lee OEM Inert Solenoid Valve
    • Solenoid Valve Opening Speed: 1-2 ms
    • Reservoirs : 5mL pressurized syringes with 3-way stop cock luer valves

Sample pressurized flow rate: 1mL in 9 minutes @ 10 PSI / 70kPa through QMM with 100μm ID tubes

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