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BA-01M – Bridge Amplifier Module

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Intracellular Bridge Mode Amplifier

  • Precise current clamp performance
  • Easy to use cell penetration mode with sharp microelectrodes
  • Compatible with any data acquisition system
  • Also available as 19″ stand-alone device

About BA-01M

The bridge amplifier module BA-01M is a wide bandwidth high impedance intracellular amplifier for recordings with sharp microelectrodes or suction (patch) pipettes. Currently, BA amplifiers are used in vertebrate (rat, mouse, cat, fish etc.) and invertebrate (leech, crab, snail, insect etc.) neurons, muscle cells, other excitable tissue and plant cells.

The BA-01M EPMS module has the same specification as the BA-01X 19″ stand-alone device except that it has only one current input range (1 nA/V), only one potential output (x10 mV), only one bridge balance range (0-1000 MΩ) and no oscillation shut-off.

Bridge amplifiers are also available as 19″ stand-alone devices.

Features

  • True current clamp operation with measured membrane potential and complete cancellation of series resistance
  • Can be used with sharp microelectrodes, and patch pipettes in the whole-cell and perforated-patch configuration
  • Digital DISPLAYS for current, voltage and electrode resistance
  • OSCILLATION SHUT-OFF unit prevents cells from damage
  • BUZZ and ELECTRODE CLEAR facility
  • Digital setting of gated stimulus amplitude, setting and digital read-out of holding current
  • Now with enhanced (x10) current range for electroporation and iontophoresis

Combine with

  • EXT-10C (extracellular amplifier module)
  • DPA-2FX (amplifier/filter module)
  • ISO-STIM 01M (stimulus isolator module)
  • TMR-02M (timer module)

and get a complete system for stimulating, extracellular and intracellular recording in one 19” rackmount cabinet

Technical Data

Headstage Input voltage range:    ±1000 mV
Operating voltage:    ±15 V
Enclosure:    Size: 23 x 70 x 26 mm, grounded
Holding bar:    Size: length 150 mm, Æ 8 mm
Electrode connector:    BNC with driven shield
Ground connector:    2.4 mm connector
REF connector (optional):    SMB connector
Input resistance:    >1013 Ω (internally adjustable)
Current range x1:    ±12 nA into 1 GΩ
Current range x10:    ±120 nA into 100 MΩElectrode parameter controls:
BIAS:    range ±200 pA, current adjustable with trim potentiometer
OFFSET:    range ±200 mV, ten-turn control
capacitance compensation:    range 0 – 30 pF, ten-turn control
Cell penetration overcompensation of capacitance compensation (BUZZ), duration ~3 – ~110 ms (dependent on the setting of capacitance compensation), timer controlled with linear control, accessible with remote switch
Electrode clear circuit Application of max. DC currents (-Imax or +Imax)
Bridge balance Adjustable with ten-turn control, 0-1000 MΩ
Electrode resistance test 10 mV / MΩ obtained by application of square current pulses ±2 nA, display XXXX MΩ
Bandwidth and speed response Full power bandwidth (REL = 10 kW):    >10 kHz, rise time (10% – 90%)
(Square pulse, 1V pp)    40 µs (voltage), 30 µs (current) (REL = 100 MΩ)
25 µs (voltage and current) (REL = 5 MΩ)
Outputs Resistance:    50 Ω
Current x1:    BNC connector, sensitivity 1 nA / V, display XX.XX nA, resolution 10 pA
Current x10:    BNC connector, sensitivity 0.1 nA / V, display XXX.X nA, resolution 100 pA
Potential:    BNC connector, sensitivity x10 mV, display XXXX mV
Inputs Current x1:
Current stimulus input via BNC connector, sensitivity 1 nA / V
Step gate input via BNC connector, gated stimulus with digital control of current step size (X.XX nA). Max. step size: 9.99 nA, resolution: 10 pA; polarity selectable with toggle switch, holding current range: ±10 nA, adjustable with ten-turn control
Current x10:
Current stimulus input via BNC connector, sensitivity 10 nA / V
Step gate input via BNC connector, gated stimulus with digital control of current step size, (XX.X nA). Max. step size: 99.9 nA, resolution: 100 pA; polarity selectable with toggle switch, holding current range: ±100 nA, adjustable with ten-turn control
Dimensions Front panel:    24 HP (121.5 mm) x 3U (128.5 mm)
Housing:    7” (175 mm) deep

Downloads

Manual BA-01M manual
Brochure BA-Series

 

About BA-01M

About BA-01M

The bridge amplifier module BA-01M is a wide bandwidth high impedance intracellular amplifier for recordings with sharp microelectrodes or suction (patch) pipettes. Currently, BA amplifiers are used in vertebrate (rat, mouse, cat, fish etc.) and invertebrate (leech, crab, snail, insect etc.) neurons, muscle cells, other excitable tissue and plant cells.

The BA-01M EPMS module has the same specification as the BA-01X 19″ stand-alone device except that it has only one current input range (1 nA/V), only one potential output (x10 mV), only one bridge balance range (0-1000 MΩ) and no oscillation shut-off.

Bridge amplifiers are also available as 19″ stand-alone devices.

Features

Features

  • True current clamp operation with measured membrane potential and complete cancellation of series resistance
  • Can be used with sharp microelectrodes, and patch pipettes in the whole-cell and perforated-patch configuration
  • Digital DISPLAYS for current, voltage and electrode resistance
  • OSCILLATION SHUT-OFF unit prevents cells from damage
  • BUZZ and ELECTRODE CLEAR facility
  • Digital setting of gated stimulus amplitude, setting and digital read-out of holding current
  • Now with enhanced (x10) current range for electroporation and iontophoresis

Combine with

  • EXT-10C (extracellular amplifier module)
  • DPA-2FX (amplifier/filter module)
  • ISO-STIM 01M (stimulus isolator module)
  • TMR-02M (timer module)

and get a complete system for stimulating, extracellular and intracellular recording in one 19” rackmount cabinet

Technical Data

Technical Data

Headstage Input voltage range:    ±1000 mV
Operating voltage:    ±15 V
Enclosure:    Size: 23 x 70 x 26 mm, grounded
Holding bar:    Size: length 150 mm, Æ 8 mm
Electrode connector:    BNC with driven shield
Ground connector:    2.4 mm connector
REF connector (optional):    SMB connector
Input resistance:    >1013 Ω (internally adjustable)
Current range x1:    ±12 nA into 1 GΩ
Current range x10:    ±120 nA into 100 MΩElectrode parameter controls:
BIAS:    range ±200 pA, current adjustable with trim potentiometer
OFFSET:    range ±200 mV, ten-turn control
capacitance compensation:    range 0 – 30 pF, ten-turn control
Cell penetration overcompensation of capacitance compensation (BUZZ), duration ~3 – ~110 ms (dependent on the setting of capacitance compensation), timer controlled with linear control, accessible with remote switch
Electrode clear circuit Application of max. DC currents (-Imax or +Imax)
Bridge balance Adjustable with ten-turn control, 0-1000 MΩ
Electrode resistance test 10 mV / MΩ obtained by application of square current pulses ±2 nA, display XXXX MΩ
Bandwidth and speed response Full power bandwidth (REL = 10 kW):    >10 kHz, rise time (10% – 90%)
(Square pulse, 1V pp)    40 µs (voltage), 30 µs (current) (REL = 100 MΩ)
25 µs (voltage and current) (REL = 5 MΩ)
Outputs Resistance:    50 Ω
Current x1:    BNC connector, sensitivity 1 nA / V, display XX.XX nA, resolution 10 pA
Current x10:    BNC connector, sensitivity 0.1 nA / V, display XXX.X nA, resolution 100 pA
Potential:    BNC connector, sensitivity x10 mV, display XXXX mV
Inputs Current x1:
Current stimulus input via BNC connector, sensitivity 1 nA / V
Step gate input via BNC connector, gated stimulus with digital control of current step size (X.XX nA). Max. step size: 9.99 nA, resolution: 10 pA; polarity selectable with toggle switch, holding current range: ±10 nA, adjustable with ten-turn control
Current x10:
Current stimulus input via BNC connector, sensitivity 10 nA / V
Step gate input via BNC connector, gated stimulus with digital control of current step size, (XX.X nA). Max. step size: 99.9 nA, resolution: 100 pA; polarity selectable with toggle switch, holding current range: ±100 nA, adjustable with ten-turn control
Dimensions Front panel:    24 HP (121.5 mm) x 3U (128.5 mm)
Housing:    7” (175 mm) deep

Downloads

Downloads

Manual BA-01M manual
Brochure BA-Series